RESEARCH

We work at the convergence between neuroscience and engineering by taking advantage of an interdisciplinary approach to solve important emerging problems in translational neuroengineering, especially in the development of high-throughput technologies and screening platforms for the discovery of novel therapeutic targets.

BIOHYBRID ELECTRONICS

Cutting-edge innovation in biohybrid electronics offers new possibilities for diagnosis, treatment, and patient care, because of their ability to merge biological and electronic systems, providing unique advantages including: 1) responsive interaction with biological elements in living organisms, 2) substantially enhanced biocompatibility to reduce immune responses and improving long-term functionality, 3) flexible and adaptable construction to for functional and structural conformation to complex in vivo environments, 4) possibility to detect and manipulate multi-modal biological signals to allow personalized/precision medicine.

CONDUCTIVE and SEMI-CONDUCTIVE HYDROGEL for MULTI-MODAL BIOSENSING and SMART THERAPY

ORGANIC ELECTRONIC DEVICES for ENHANCED IN-BODY GENE DELIVERY and GENE EDITING

ADVANCED BRAIN-COMPUTER-INTERFACES

Advanced brain-computer interfaces (BCIs) are rapidly evolving, we are working to create BCIs 1) to improve signal acquisition for capturing detailed brain activity; 2) to develop non-invasive brain modulation methods; 3) to use sophisticated algorithms to decode brain signals allowing for precise prosthetic control or communication aids; 4) to leverage neuroplasticity for rehabilitation, motor restoration and even mood and cognitive enhancement.

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BIOHYBRID ELECTRONICS FOR NEXT-GENERATION BCI

Novel biohybrid electronics enables the creation of next-generation brain-computer-interface for both therapy and meta-interaction.

TECHNOLOGY FOR REMOTE CONTROL OF BRAIN FUNCTION

The capability to modulate neural processes is crucial for studying brain function. We develop technologies to address this challenge as exemplified by a success in remote control of rodent brain by using nanofabrication and upconversion techniques.

HIGH-THROUGHPUT FUNCTIONAL SCREENING TECHNOLOGY

Different high-throughput technologies are developed at MINE-lab for therapeutics or genetics discovery. Our approach is to rapidly assess the biological activity of a large number of potent elements, which would otherwise be time or cost prohibitive for existing methods.

HIGH-THROUGHPUT BAMING AND MACHINE LEARNING

Combination of whole brain activity mapping with machine learning for a shortcut for drug discovery and repositioning.

NANOPROBE STRUCTURED BIOCHIP

Nanoprobe structured Biochip Technology enables low-cost solution for diagnostic transcriptomic analysis.