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NEWS

Stay Informed About MINE-Lab

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New Publication
nature biomedical egnineering

19 July, 2026

Sequencing free spatial profiling of post-transcriptional regulation in fresh tissues using nanoneedle arrays

 

Spectrum-FISH: reimagining spatial omics for the clinic

New Publication
Science Advances

19 June, 2026

Electronics with Switchable Flexibility for 3D Conforming Neural Interfaces.

Congratulations to Xingdao and Matthew! 

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New Publication
nature reviews bioengineering

09 June, 2026

Clinical translation of spatial omics

Humbled to join the clinical pathology experts to share a bit of our thoughts on translating spatial omics for clinical applications.

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Award
Best Paper on Materials 2026

09 June, 2026

Xingdao and Matthew won 1st Runner-up

BEST PAPER ON MATERIALS 2026 for their

work about Electronics with Switchable Flexibility

The compeition is hosted by Hong Kong Institution of Engineers (HKIE)

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New Publication
National Science Review

April, 2026

Ultrathin and ultrastrong hydrogel bioelectronic membranes

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Award

March, 2026

Our invention of the nanostructured biochip was awarded a Gold Medal with Jury Congratulations at the 51st Geneva International Exhibition of Inventions 2026.. 

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New Publication
ACS Sensors

Feb, 2026

Colorimetric Sensing of MicroRNAs in Whole Blood for Early Diagnosis of Heart Failure. 

Congratulations to Youyang!

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Award

December  13, 2025

Congratulations to Guo Feng, won the 2025 Young Scientist Award in Life Science, Hong Kong Insitituion of Science

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New publication
Science Advances

Nov 19, 2025

High-strength and fracture-resistant ionogels via solvent-tailored interphase cohesion in nanofibrous composite networks.

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New publication
Biomaterials

Nov 19, 2025

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Commentary: Therapeutic Seizure Monitoring: A Closed-Loop Device for Direct Delivery of Antiseizure Therapeutics

March 25, 2025

An independent commentary to our work of closed-loop neurotherapy.

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HYDROGEL ELECTRONICS FOR CLOSED-LOOP NEUROTHERAPY

Nov 22, 2024

Congratulations to Qu Jin and Xie Kai,  our work on Hydrogel Electronics for Closed-Loop Neurotherapy is published on Science Advances.

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IN VIVO GENE EDITING  OF T-CELLS FOR ENHANCED IMMUNOTHERAPY

Nov 7, 2024

Congratulations to Jin Qu and Yuan Wang  for a new publication accepted by Nature Communications. We created a hydrogel electronics-based tweezer system to perform in vivo gene editing of T-cells in lymph-nodes to enhance cancer immunotherapy. 

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SINGLE-CELL GENE SILENCING FOR COMBINATORY SIRNA SCREENING

Oct 26, 2024

Congratulations to Guo Feng and Ji Xianglin, our work on single-cell gene silencing for combinatory siRNA screening is accepted for publication on Nature Communications.

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MEDIA COVERAGE

Oct 8, 2024

Professor Shi was interviewed by Wenweipo to comment on the 2024 Nobel Prize in Physiology or Medicine. Our biochip technology for non-PCR, sequencing-free, highly multiplexed, and high-throughput profiling of microRNAs was patented by US patent office in 2023 May.

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BEYOND RESEARCH

Sept 9, 2024

Professor Shi, as the invited panel member, attended the seminar (Hong Kong as Asia’s Medical Technology Hub) hosted by InvestHK, to discuss the exploration of Hong Kong's pivotal role in the medical device industry and to discover the opportunities available for medical device companies and stay informed about regulatory requirements for medical device registration in Hong Kong

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META LEARNING AND BRAIN ACTIVITY MAPPING FOR DRUG DISCOVERY

Oct 18, 2024

Congratulations to Luo Xuan for a publication on iScience. We integrate few-shot meta-learning algorithms with brain activity mapping (BAMing) to enhance the discovery of therapeutics for brain diseases. 

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NEW METHOD FOR ANALYSING EPIGENETIC TARGETS

July 17, 2024

In our new publication in JACS, we introduced a molecular beacon-functionalized nanoneedle array designed for spatially resolved profiling of long non-coding RNA and RNA-biding protein interactions.

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MICROARRAYED ELECTROPORATION FOR TRANSDERMAL DNA VACCINATION

June 12, 2024

Congratulations to Yuan Wang and Jin Qu for their publication in PNAS. We develop a hydrogel-based organic electronic device (μEPO) for both transdermal delivery of nucleic acids and in vivo microarrayed cell electroporation, which is specifically oriented toward one-step transfection of DNAs in subcutaneous antigen-presenting cells (APCs) for cancer immunotherapy.

©2024 by Multiscale Integrative NeuroEngineering Laboratory.

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